When you are diagnosed with dysplasia or LSIL / HSIL after a PAP smear, you probably have so many questions flying around your head and feel as if you can't think straight. What does this diagnosis mean for you?

Diagnosis of Dysplasia and/or LSIL / HSIL

The term "dysplasia" is used in medicine to refer to an abnormal development or growth of cell tissues and organs.

When you are diagnosed with dysplasia after your gynaecological cancer screening, the so-called PAP smear, it means that some cervix cells show aberrations. These cell changes are caused by the human papilloma virus (HPV).

LSIL / HSIL stands for mild to moderate cell changes of the cervix. 750,000 women are diagnosed with LSIL / HSIL in Germany each year.

LSIL / HSIL: Do I have cancer?

LSIL / HSIL isn't cancer. Also, many patients (8 out of 10) won't get cancer as the cell changes will heal on their own - surgery is not necessary. In most cases, a conization is not necessary.

What can I do now?

Cell changes are caused by HPV (human papilloma viruses).

Your gynecologist will run an HPV test to find out whether there are any high-risk types of the human papilloma virus. If high-risk types of the HPV have been detected, dysplasia can aggravate so that a cervical conization will be necessary.

But there is also good news: In most patients, the immune system recognizes and attacks HPV. A certain protein, the "L1 capsid protein" must be present in the cell nucleus of HPV - this protein activates the immune system. If the protein is detected, about 80 % of the dysplasia will regress to normal within one year.

The cytoactiv®test can easily prove the existence of L1 capsid protein and the positive mobilization of the immune system.

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